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Publications in 2022

Publications are the primary method for reporting and long-term documentation of the research conducted at the NIPER-Hyderabad. Here the list of publications published in year wise...


  1. Dhiman, V.; Patil, K.; Velip, L.; Talluri, M. K.; Gananadhamu, S. Comprehensive degradation profiling and influence of different oxidizing reagents on tinoridine hydrochloride: Structural characterization of its degradation products using HPLC and HRMS. Rapid Communications in Mass Spectrometry 2022, 36 (1), e9210. https://doi.org/10.1002/rcm.9210
  2. Dhiman, V.; Singh, S.; Balhara, A.; Kushwah, B. S.; Velip, L.; Golla, V. M.; Samanthula, G. Stress degradation study on entrectinib and characterization of its degradation products using HRMS and NMR. Journal of Pharmaceutical and Biomedical Analysis 2022, 208, 114459. https://doi.org/10.1016/j.jpba.2021.114459
  3. Velip, L.; Dhiman, V.; Kushwah, B. S.; Golla, V. M.; Gananadhamu, S. Identification and characterization of urapidil stress degradation products by LC-Q-TOF-MS and NMR: Toxicity prediction of degradation products. Journal of Pharmaceutical and Biomedical Analysis 2022, 211, 114612. https://doi.org/10.1016/j.jpba.2022.114612
  4. Kushwah, B. S.; Golla, V. M.; Dhiman, V.; Samanthula, G.. Forced degradation studies on axitinib and characterization of its degradation products by liquid chromatography-high resolution mass spectrometry and nuclear magnetic resonance spectroscopy along with its in silico toxicity assessment. Separation Science Plus 2022, 5 (8), 431–441. https://doi.org/10.1002/sscp.20220004
  5. Kushwah, B. S.; Padhy, H. P.; Khemchandani, R.; Golla, V. M.; Kanchupalli, V. K.; Sonti, R.; Samanthula, G.. Structural characterization of novel hydrolytic and oxidative degradation products of acalabrutinib by LC-Q-TOF-MS, H/D exchange and NMR. Journal of Pharmaceutical and Biomedical Analysis 2022, 221, 115077. https://doi.org/10.1016/j.jpba.2022.115077
  6. Kushwah, B. S.; Velip, L. G.; Bharani, K. K.; Surya, P. V.; Sinha, S.; Khurana, A.; Kankarne, Y.; Banothu, A. K.; Gananadhamu, S. A sensitive method for determination of nimesulide and its hydroxy metabolite in milk using validated UPLC-MS method. Talanta Open 2022, 6, 100160. https://doi.org/10.1016/j.talo.2022.100160
  7. Vambhurkar, G.; Amulya, E.; Sikder, A.; Shah, S.; Famta, P.; Khatri, D. K.; Singh, S. B.; Srivastava, S. Nanomedicine Based Potentially Transformative Strategies for Colon Targeting of Peptides: State-of-the-Art. Colloids and Surfaces B: Biointerfaces 2022, 219, 112816. https://doi.org/10.1016/j.colsurfb.2022.112816
  8. Singh, G.; Pushpa, T. K.; Gupta, S. K.; Srivastava, S.; Khatri, D. K.; Singh, S. B. Perspective on Cav-1 for Its Potential as Newer Therapeutics for Parkinson’s Disease. CNS & Neurological Disorders - Drug Targets 2022, 22, 1429–1438. https://doi.org/10.2174/1871527321666220909150406
  9. Kushwah, B. S.; Padhy, H. P.; Khemchandani, R.; Golla, V. M.; Kanchupalli, V. K.; Sonti, R.; Samanthula, G. Structural Characterization of Novel Hydrolytic and Oxidative Degradation Products of Acalabrutinib by LC-Q-TOF-MS, H/D Exchange and NMR. Journal of Pharmaceutical and Biomedical Analysis 2022, 221, 115077. https://doi.org/10.1016/j.jpba.2022.115077
  10. Gajula, S. N. R.; Nathani, T. N.; Patil, R. M.; Talari, S.; Sonti, R. Aldehyde Oxidase Mediated Drug Metabolism: An Underpredicted Obstacle in Drug Discovery and Development. Drug Metabolism Reviews 2022, 54, 427. https://doi.org/10.1080/03602532.2022.2144879
  11. Dhurjad, P.; Dhalaram, C. S.; Ali, N.; Kumari, N.; Sonti, R. Metal-Organic Frameworks in Chiral Separation of Pharmaceuticals. Chirality 2022, 34, 1419–1436. https://doi.org/10.1002/chir.23499
  12. Sahoo, S. K.; Gajula, S. N. R.; Ahmad, M. N.; Kaul, G.; Nanduri, S.; Sonti, R.; Dasgupta, A.; Chopra, S.; Yaddanapudi, V. M. Bioevaluation of Quinoline-4-Carbonyl Derivatives of Piperazinyl-Benzothiazinones as Promising Antimycobacterial Agents. Archiv der Pharmazie 2022, 11, 2200168. https://doi.org/10.1002/ardp.202200168
  13. Gajula, S. N. R.; Vora, S. A.; Dikundwar, A. G.; Sonti, R. In Vitro Drug Metabolism Studies Using Human Liver Microsomes. IntechOpen 2022. https://doi.org/10.5772/intechopen.108246
  14. Anchi, P.; Chilvery, S.; Tekalkar, S.; Gajula, S. N. R.; Sonti, R.; Godugu, C. Nimbolide Loaded Sustained Release Microparticles as Single-Dose Formulations for Effective Management of Arthritis. Journal of Drug Delivery Science and Technology 2022, 75, 103638. https://doi.org/10.1016/j.jddst.2022.103638
  15. Moi, S.; Shekh, S.; Reddy, K. K. A.; Dhurjad, P.; Sonti, R.; Gowd, K. H. Peptide Cysteine Thiols Act as Photostabilizer of Avobenzone through Stabilizing the Transition State of Keto-Enol Tautomerization. Photochemistry and Photobiology 2022. https://doi.org/10.1111/php.13691
  16. Gajula, S. N. R.; Navin, N. T.; Talari, S.; Shende, C.; Sonti, R. Green Bioanalysis: An Innovative and Eco-Friendly Approach for Analyzing Drugs in Biological Matrices. Bioanalysis 2022, 12, 881. https://doi.org/10.4155/bio-2022-0095
  17. Dandekar, M. P.; Palepu, M. S. K.; Satti, S.; Jaiswal, Y.; Singh, A. A.; Dash, S. P.; Gajula, S. N. R.; Sonti, R. Multi-Strain Probiotic Formulation Reverses Maternal Separation and Chronic Unpredictable Mild Stress-Generated Anxiety- and Depression-Like Phenotypes by Modulating Gut Microbiome–Brain Activity in Rats. ACS Chemical Neuroscience 2022, 13, 1948. https://doi.org/10.1021/acschemneuro.2c00143
  18. Santosh, K. S.; Sarvan, M.; Siva, N. R. G.; Mohammad, N. A.; Grace, K.; Srinivas, N.; Sonti, R.; Dasgupta, A.; Chopra, S.; Yaddanapudi, V. M. Identification of Nitrofuranylchalcone Tethered Benzoxazole-2-Amines as Potent Inhibitors of Drug Resistant Mycobacterium tuberculosis Demonstrating Bactericidal Efficacy. Bioorganic & Medicinal Chemistry 2022, 64, 116777. https://doi.org/10.1016/j.bmc.2022.116777
  19. Grzesiek, S.; Paladini, J.; Habazettl, J.; Sonti, R. Imatinib Disassembles the Regulatory Core of Abelson Kinase by Binding to Its ATP Site and Not by Binding to Its Myristoyl Pocket. Magnetic Resonance 2022, 3, 1. https://doi.org/10.5194/mr-3-91-2022
  20. Gaurav, P.; Shaik, M. G.; Swayamsiddha, K.; Sai, M. C.; Dannarm, S. R.; Jitendra, G.; Sonti, R.; Srinivas, N. SmI2-Mediated C-Alkylation of Ketones with Alcohols in Microwave Conditions: A Novel Route to Alkylated Ketones. Chemistry – An Asian Journal 2022, 17, 8. https://doi.org/10.1002/asia.202200041
  21. Makhal, P. N.; Dannarm, S. R.; Shaikh, A. S.; Sonti, R.; Kaki, V. R. TBHP-Mediated Selenocyclization of N-Allylbenzamides/Benzthioamides via In-Situ Generation of “PhSeOH” Species. ChemistrySelect 2022, 7, 14. https://doi.org/10.1002/slct.202200933
  22. Gaurav, P.; Shaik, M. G.; Swanand, V. J.; Preeti, R.; Swayamsiddha, K.; Mahesh, P. S.; Dannarm, S. R.; Sonti, R.; Srinivas, N. Cu(I)-Catalyzed Microwave-Assisted Multicomponent Reaction Towards Synthesis of Diverse Fluorescent Quinazolino[4,3-b]Quinazolin-8-Ones and Their Photophysical Study. ChemistrySelect 2022, 7, 14. https://doi.org/10.1002/slct.202200500
  23. Dhurjad, P.; Dhavaliker, C.; Gupta, K.; Sonti, R. Exploring Drug Metabolism by the Gut Microbiota: Modes of Metabolism and Experimental Approaches. Drug Metabolism and Disposition 2022, 50, 224. https://doi.org/10.1124/dmd.121.000669