Publications in 2024
Publications are the primary method for reporting and long-term documentation of the research conducted at the NIPER-Hyderabad. Here the list of publications published in year wise...
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Kabra, P.; Sakla, A. P.; Kumar, M.; Sathish, M.; Laxmikeshav, K.; Dandekar, M. P.; Shankaraiah, N.
Regiospecific Synthesis of Thioether-Linked 3-Hydroxyoxindoles from Spiro-Epoxy Oxindoles as Cytotoxic and Tubulin Polymerization Inhibitors.
ChemistrySelect 2024, 9, e202404458.
https://doi.org/10.1002/slct.202404458
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Kumawat, A.; Mansuri, S.; Galla, M. S.; Shankaraiah, N.
KSCN-Mediated One-Pot Thiocyanation Tandem Cyclization of Enaminones: A Facile Access to 2-Amino/Imino Thiazolo Fused Chromone and Coumarin Frameworks.
European Journal of Organic Chemistry 2024, 27, e202400690.
https://doi.org/10.1002/ejoc.202400690
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Khan, M. A.; Reddyrajula, R.; Sakla, A. P.; Sathish, M.; Shankaraiah, N.
Microwave-Assisted One-Pot Synthesis of Tetrahydro-β-Carbolines by Fe(II)-Catalyst: Utilizing Methanol as Methylene Synthon.
Asian Journal of Organic Chemistry 2024, 13, e202400404.
https://doi.org/10.1002/ajoc.202400404
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Valapil, D. G.; Devabattula, G.; Sakla, A. P.; Godugu, C.; Shankaraiah, N.
Design, Development of Pyrazole-Linked Spirocyclopropyloxindole-Carboxamides as Potential Cytotoxic Agents and Selective Type III Allosteric VEGFR-2 Inhibitors.
ChemMedChem 2024, 19, e202400422.
https://doi.org/10.1002/cmdc.202400422
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Khan, M. A.; Sharma, A.; Bora, D.; Sindhuja, R. H.; Phanindranath, R.; Nagesh, N.; Shankaraiah, N.
Development of β-Carboline-Coumarin Based Hybrids as Potential Cytotoxic and Topoisomerase IIα Inhibitors.
ChemistrySelect 2024, 9, e202401682.
https://doi.org/10.1002/slct.202401682
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Madhurya, M. S.; Thakur, V.; Dastari, S.; Shankaraiah, N.
Pyrrolo[2,3-d]pyrimidines as Potential Kinase Inhibitors in Cancer Drug Discovery: A Critical Review.
Bioorganic Chemistry 2024, 153, 107867.
https://doi.org/10.1016/j.bioorg.2024.107867
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Galla, M. S.; Kale, N.; Sharma, A.; Hajre, A.; Godugu, C.; Shankaraiah, N.
Development of Chromone-Thiazolidine-2,4-Dione Knoevenagel Conjugates as Apoptosis Inducing Agents.
Bioorganic & Medicinal Chemistry Letters 2024, 109, 129853.
https://doi.org/10.1016/j.bmcl.2024.129853
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Dastari, S.; Murugappan, S.; John, S. E.; Shankaraiah, N.
Microwave-Assisted Ru(II)-Catalyzed Regioselective Methyl Acylation of 2-Arylbenzoazoles: Synthesis of Benzofuran Conjugates via C−H Activation/Annulation.
Journal of Organic Chemistry 2024, 89, 7027–7035.
https://doi.org/10.1021/acs.joc.4c00402
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Sakla, A. P.; Bazaz, M. R.; Mahale, A.; Sharma, P.; Valapil, D. G.; Kulkarni, O. P.; Dandekar, M. P.; Shankaraiah, N.
Development of Benzimidazole-Substituted Spirocyclopropyl Oxindole Derivatives as Cytotoxic Agents: Tubulin Polymerization Inhibition and Apoptosis Inducing Studies.
ChemMedChem 2024, 19, e202400052.
https://doi.org/10.1002/cmdc.202400052
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Mishra, P.; Sharma, N.; Galla, M. S.; Shankaraiah, N.
Recent Insights of PROTAC Developments in Inflammation-Mediated and Autoimmune Diseases: A Critical Review.
RSC Medicinal Chemistry 2024, 15, 2585–2600.
https://doi.org/10.1039/d4md00142g
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Galla, M. S.; Kale, N. B.; Kumawat, A.; Bora, D.; Shankaraiah, N.
Rh(III)-Catalysed C–H Annulation of cis-Stilbene Acids with 2-Diazo-1,3-Diketones: Facile Access to 6,7-Dihydrobenzofuran-4(5H)-one and α-Pyrone Scaffolds.
Organic & Biomolecular Chemistry 2024, 22, 3933–3939.
https://doi.org/10.1039/d4ob00151f
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Murugappan, S.; Jungare, K.; Dastari, S.; Barve, N. M.; Shankaraiah, N.
Hydrazide-Hydrazone/Hydrazone as Enabling Linkers in Anti-Cancer Drug Discovery: A Comprehensive Review.
Journal of Molecular Structure 2024, 1307, 138012.
https://doi.org/10.1016/j.molstruc.2024.138012
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Valapil, D. G.; Shankaraiah, N.
Spirooxindole Derivatives as Kinase Based Anti-Cancer Agents.
In Spirooxindole: Chemistry, Synthesis, Characterization and Biological Significance; Elsevier, 2024; 1st Edition. ISBN: 978-0-443-22324-2.
https://doi.org/10.1016/B978-0-443-22324-2.00017-5
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Golla, V. M.; Kalyan, M.; Gholap, U.; Padhy, H. P.; Ramachandran, R. K.; Samanthula, G.
Discerning the stability behaviour of mavacamten availing liquid chromatography-mass spectrometry and nuclear magnetic resonance spectroscopy: In silico toxicity and mutagenicity prediction of degradation products.
Journal of Mass Spectrometry 2024, 59 (3), e5007.
https://doi.org/10.1002/jms.5007
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Pilli, P.; Kommalapati, H. S.; Golla, V. M.; Khemchandani, R.; Ramachandran, R. K.; Samanthula, G.
Covalent organic frameworks: Spotlight on applications in the pharmaceutical arena.
Bioanalysis 2024, 16 (8), 279–305.
https://doi.org/10.4155/bio-2023-0256
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Chaganti, S.; Kushwah, B. S.; Velip, L.; Tiwari, S. S.; Chilvery, S.; Godugu, C.; Samanthula, G.
In vivo and in vitro metabolite profiling of nirmatrelvir using LC–Q‐ToF–MS/MS along with the in silico approaches for prediction of metabolites and their toxicity.
Biomedical Chromatography 2024, 38 (5), e5849.
https://doi.org/10.1002/bmc.5849
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Golla, V. M.; Khemchandani, R.; Chaganti, S.; Samanthula, G.
Separation and characterization of hydrolytic degradation product of deucravacitinib by validated high-performance liquid chromatography method and liquid chromatography-mass spectrometry.
Separation Science Plus 2024, 7 (5), 2300180.
https://doi.org/10.1002/sscp.202300180
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Chaganti, S.; Chauhan, U.; Bhatt, N.; Kommalapati, H.; Golla, V. M.; Pilli, P.; Samanthula, G.
LC-HRMS and NMR studies for the characterization of degradation impurities of ubrogepant along with the in silico approaches for the prediction of degradation and toxicity.
Journal of Pharmaceutical and Biomedical Analysis 2024, 243, 116117.
https://doi.org/10.1016/j.jpba.2024.116117
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Chaganti, S.; Nelapati, C.; Jain, D.; Roshitha, K.; Kanchupalli, V.; Samanthula, G.
Separation and characterization of degradation impurities of upadacitinib by liquid chromatography and high resolution mass spectrometry.
Journal of Chromatography B 2024, 1247, 124319.
https://doi.org/10.1016/j.jchromb.2024.124319
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Nizam, M. V. P.; Yerram, S.; Patnam, J. D.; A. C. S.; Aglave, G.; Joga, R.; Raghuvanshi, R. S.; Srivastava, S.
Ensuring Product Safety: A Comprehensive Retrospective Study of USFDA Drug Recalls (2019–2023).
Journal of Pharmaceutical Innovation 2024, 19.
https://doi.org/10.1007/s12247-024-09869-z
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Behera, H. K.; Joga, R.; Yerram, S.; Karnati, P.; Mergu, T.; Gandhi, K.; M, S.; Nathiya, D.; Singh, R. P.; Srivastava, S.; Kumar, S.
Exploring the Regulatory Framework of Psychedelics in the US & Europe.
Asian Journal of Psychiatry 2024, 102, 104242.
https://doi.org/10.1016/j.ajp.2024.104242
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Aglave, G.; Yerram, S.; Patnam, J. D.; Ajmal, C. S.; Nizam, V. P. M.; Joga, R.; Raghuvanshi, R. S.; Srivastava, S.
Proactive Approaches to cGMP Compliance: Insights and Key Takeaways from USFDA Warning Letters to Pharmaceutical Industries Between 2019 and 2024.
Journal of Pharmaceutical Innovation 2024, 19.
https://doi.org/10.1007/s12247-024-09857-3
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Abishek; Muskan; Srivastava, S.; Prasad, P.; Kumar, S.
FDA Approval of Zituvio for Type 2 Diabetes.
Current Indian Science 2024, 02.
https://doi.org/10.2174/012210299x286824240722042737
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Kirthiga, D.; Joga, R.; Srivastava, S.; Nagpal, K.; Dhamija, I.; Grover, P.; Kumar, S.
Regulatory Landscape and Challenges in CAR-T Cell Therapy Development in the US, EU, Japan, and India.
European Journal of Pharmaceutics and Biopharmaceutics 2024, 201, 114361.
https://doi.org/10.1016/j.ejpb.2024.114361
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Varpe, P.; Joga, R.; Aglave, G.; Vasu, P.; Yerram, S.; Bellapu, K. K.; Srivastava, S.; Kumar, S.
Esterase Responsive Release of Anti-Cancer Agents from Conjugated Lipid Nanocarrier and the Regulatory Considerations.
Pharmaceutical Patent Analyst 2024, 13, 31–43.
https://doi.org/10.1080/20468954.2024.2347796
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Arya, D. K.; Deshpande, H.; Kumar, A.; Chidambaram, K.; Pandey, P.; Anjum, S.; Deepak, P.; Kumar, V.; Kumar, S.; Pandey, G.; Srivastava, S.; Rajinikanth, P. S.
HER-2 Receptor and αvβ3 Integrin Dual-Ligand Surface-Functionalized Liposome for Metastatic Breast Cancer Therapy.
Pharmaceutics 2024, 16.
https://doi.org/10.3390/pharmaceutics16091128
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Bhale, N. A.; Shah, S.; Jahnavi, A. S.; Vishwakarma, A.; Thakur, T. S.; Thomas, S. P.; Srivastava, S.; Dikundwar, A. G.
Three Strikingly Different Crystal Habits of Tadalafil: Design, Characterization, Pharmaceutical Performance, and Computational Studies.
Molecular Pharmaceutics 2024, 21, 6234–6244.
https://doi.org/10.1021/acs.molpharmaceut.4c00601
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Tandulje, A.; Varpe, P.; Chaugule, P.; Raghuvanshi, R. S.; Srivastava, S.
Deciphering the US Regulatory Framework: Comparison Between Oncology Biosimilars and Reference Biologics.
Seminars in Oncology 2024, 51, 135–141.
https://doi.org/10.1053/j.seminoncol.2024.08.002
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Sharma, A.; Dey, S.; Naga Sidhartha, N.; Shah, S.; Sapkal, R.; Srivastava, S.; Dikundwar, A. G.
Coamorphous Systems of Rebamipide: Selection of Amino Acid Coformers Based on Protein-Ligand Docking, In Vitro Assessment and Study of Interactions by Computational and Multivariate Analysis.
International Journal of Pharmaceutics 2024, 667, 124955.
https://doi.org/10.1016/j.ijpharm.2024.124955
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Kanaujiya, S.; Arya, D. K.; Pandey, P.; Anjum, S.; Anjum, M. M.; Ali, D.; Alarifi, S.; Srivastava, S.; Rajinikanth, P. S.; Singh, S.; Pandey, G.; Vijayakumar, M. R.; Sivakumar, S.
Resveratrol-Ampicillin Dual-Drug Loaded Polyvinylpyrrolidone/Polyvinyl Alcohol Biomimic Electrospun Nanofiber Enriched with Collagen for Efficient Burn Wound Repair.
International Journal of Nanomedicine 2024, 19, 5397–5418.
https://doi.org/10.2147/IJN.S464046
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Famta, P.; Shah, S.; Srinivasarao, D. A.; Sharma, A.; Kumar, R.; Vambhurkar, G.; Pandey, G.; Prasad, S. B.; Shinde, A.; Asthana, A.; Ratna, P. K.; Kumar, B. K.; Arya, D. K.; Rajinikanth, P. S.; Srivastava, S.
Simvastatin-Loaded Gelatin-Capped Polycaprolactone Nanoparticles for the Post-Operative Management of Breast Cancer.
Journal of Drug Delivery Science and Technology 2024, 101, 106163.
https://doi.org/10.1016/j.jddst.2024.106163
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Negi, M.; Amulya, E.; Phatale, V.; Abraham, N.; Hedaoo, A.; Srinivasarao, D. A.; Srivastava, S.
Surface Engineered Nano Architectonics: An Evolving Paradigm for Tackling Alzheimer’s Disease.
Life Sciences 2024, 358, 123155.
https://doi.org/10.1016/j.lfs.2024.123155
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Pandey, G.; Kolipaka, T.; Phatale, V.; Khairnar, P.; Abraham, N.; Shah, S.; Famta, P.; Vambhurkar, G.; Srinivasarao, D. A.; Saraf, S.; Srivastava, S.
Exploring the Potential of Nano-Biomaterials in Tissue Engineering.
Biomaterials in Nanomedicines for Targeted Therapy 2024, 31–54.
https://doi.org/10.1007/978-981-97-3925-7_2
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Phatale, V.; Kolipaka, T.; Khairnar, P.; Pandey, G.; Negi, M.; Saraf, S.; Srivastava, S.
Nano-Biomaterial-Assisted Targeted Therapy of Central Nervous System Disorders.
Biomaterials in Nanomedicines for Targeted Therapy 2024, 305–328.
https://doi.org/10.1007/978-981-97-3925-7_11
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Khairnar, P.; Phatale, V.; Shukla, S.; Tijani, A. O.; Hedaoo, A.; Strauss, J.; Verana, G.; Vambhurkar, G.; Puri, A.; Srivastava, S.
Nanocarrier-Integrated Microneedles: Divulging the Potential of Novel Frontiers for Fostering the Management of Skin Ailments.
Molecular Pharmaceutics 2024, 21, 2118–2147.
https://doi.org/10.1021/acs.molpharmaceut.4c00144
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Shinde, A.; Prasad, S. B.; Srinivasarao, D. A.; Shah, S.; Famta, P.; Khairnar, P.; Pandey, G.; Vambhurkar, G.; Hedaoo, A.; Kumar, R.; Srivastava, S.
Nano Voyagers: Pioneering a New Frontier in Cancer Treatment with Nanorobots as Drug Transporters.
Applied Materials Today 2024, 38, 102162.
https://doi.org/10.1016/j.apmt.2024.102162
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Amulya, E.; Bahuguna, D.; Negi, M.; Phatale, V.; Sikder, A.; Vambhurkar, G.; Katta, C. B.; Dandekar, M. P.; Madan, J.; Srivastava, S.
Lipid Engineered Nanomaterials: A Novel Paradigm Shift for Combating Stroke.
Applied Materials Today 2024, 38, 102194.
https://doi.org/10.1016/j.apmt.2024.102194
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Nene, S.; Vambhurkar, G.; Tryphena, K. P.; Singh, P. K.; Khatri, D. K.; Srivastava, S.
Evaluation of Preclinical Efficacy of Apremilast-Loaded Liquid Crystalline Nanoparticulate Gel in Amelioration of Atopic Dermatitis.
Journal of Drug Delivery Science and Technology 2024, 96, 105653.
https://doi.org/10.1016/j.jddst.2024.105653
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Pandey, G.; Phatale, V.; Khairnar, P.; Kolipaka, T.; Shah, S.; Famta, P.; Jain, N.; Srinivasarao, D. A.; Rajinikanth, P. S.; Raghuvanshi, R. S.; Srivastava, S.
Supramolecular Self-Assembled Peptide-Engineered Nanofibers: A Propitious Proposition for Cancer Therapy.
International Journal of Biological Macromolecules 2024, 256, 128452.
https://doi.org/10.1016/j.ijbiomac.2023.128452
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Pandey, G.; Kolipaka, T.; Srinivasarao, D. A.; Abraham, N.; Tickoo, V.; Khatri, D. K.; Raghuvanshi, R. S.; Srivastava, S.
Nanotechnology Invigorated Drug Delivery and Tissue Engineering Strategies for the Management of Diabetic Foot Ulcers: Therapeutic Approaches and Clinical Applications.
Journal of Drug Delivery Science and Technology 2024, 96, 105665.
https://doi.org/10.1016/j.jddst.2024.105665
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Kolipaka, T.; Pandey, G.; Abraham, N.; Srinivasarao, D. A.; Raghuvanshi, R. S.; Rajinikanth, P. S.; Tickoo, V.; Srivastava, S.
Stimuli-Responsive Polysaccharide-Based Smart Hydrogels for Diabetic Wound Healing: Design Aspects, Preparation Methods and Regulatory Perspectives.
Carbohydrate Polymers 2024, 324, 121537.
https://doi.org/10.1016/j.carbpol.2023.121537
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Khairnar, P.; Kolipaka, T.; Pandey, G.; Phatale, V.; Shah, S.; Srinivasarao, D. A.; Saraf, S.; Srivastava, S.
Nanosponge-Mediated Oligonucleotide Delivery: A Cutting-Edge Technology towards Cancer Management.
Journal of Drug Delivery Science and Technology 2024, 91, 105226.
https://doi.org/10.1016/j.jddst.2023.105226
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Vambhurkar, G.; Famta, P.; Shah, S.; Jain, N.; Srinivasarao, D. A.; Sharma, A.; Shahrukh, S.; Khatri, D. K.; Singh, S. B.; Srivastava, S.
Quality by Design Galvanized Development of Resveratrol Loaded PLGA Nanoparticles: In Vitro and Ex Vivo Evaluation for the Non-Invasive Treatment of Metastatic Melanoma.
Journal of Drug Delivery Science and Technology 2024, 91, 105252.
https://doi.org/10.1016/j.jddst.2023.105252
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Shah, S.; Famta, P.; Srinivasarao, D. A.; Shahrukh, S.; Jain, N.; Shinde, A.; Prasad, S. B.; Vambhurkar, G.; Pandey, G.; Kumar, R.; Saraf, S.; Srivastava, S.
Nanomedicine-RNAi Interface: Architypes in Prostate Cancer Therapeutics.
Journal of Drug Delivery Science and Technology 2024, 92, 105349.
https://doi.org/10.1016/j.jddst.2024.105349
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Nooreen, R.; Nene, S.; Vambhurkar, G.; Srivastava, S.
Transdermal Delivery and Exploration of Preclinical Anti-Rheumatoid Efficacy of Pirfenidone Embedded Nanoemulgel in Adjuvant-Induced Rat Model.
Journal of Drug Delivery Science and Technology 2024, 93, 105428.
https://doi.org/10.1016/j.jddst.2024.105428
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Shah, S.; Famta, P.; Kumar, R.; Sharma, A.; Vambhurkar, G.; Pandey, G.; Singh, G.; Kumar, P.; Mehra, A.; Mourya, A.; Srinivasarao, D. A.; Shinde, A.; Prasad, S. B.; Khatri, D. K.; Madan, J.; Srivastava, S.
Quality by Design Fostered Fabrication of Cabazitaxel Loaded pH-Responsive Improved Nanotherapeutics Against Prostate Cancer.
Colloids and Surfaces B: Biointerfaces 2024, 234, 113732.
https://doi.org/10.1016/j.colsurfb.2023.113732
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Shahrukh, S.; Jain, N.; Shah, S.; Famta, P.; Vambhurkar, G.; Srinivasarao, D. A.; Sharma, A.; Kumar, R.; Shinde, A.; Prasad, S. B.; Singh, S. B.; Srivastava, S.
Quality by Design Enabled Tumor Microenvironment-Responsive Simvastatin-Loaded Liposomes for Prostate Cancer Management.
Journal of Drug Delivery Science and Technology 2024, 94, 105474.
https://doi.org/10.1016/j.jddst.2024.105474
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Manchanda, N.; Vishkarma, H.; Goyal, M.; Shah, S.; Famta, P.; Talegaonkar, S.; Srivastava, S.
Surface Functionalized Lipid Nanoparticles in Promoting Therapeutic Outcomes: An Insight View of the Dynamic Drug Delivery System.
Current Drug Targets 2024, 25, 278–300.
https://doi.org/10.2174/0113894501285598240216065627
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Abraham, N.; Kolipaka, T.; Pandey, G.; Negi, M.; Srinivasarao, D. A.; Srivastava, S.
Revolutionizing Pancreatic Islet Organoid Transplants: Improving Engraftment and Exploring Future Frontiers.
Life Sciences 2024, 343, 122545.
https://doi.org/10.1016/j.lfs.2024.122545
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Shah, S.; Famta, P.; Vambhurkar, G.; Bagasariya, D.; Kumar, K. C.; Srinivasarao, D. A.; Begum, N.; Sharma, A.; Shahrukh, S.; Jain, N.; Khatri, D. K.; Srivastava, S.
Sulfo-Butyl Ether β-Cyclodextrin Inclusion Complexes of Bosutinib: In Silico, In Vitro and In Vivo Evaluation in Attenuating the Fast-Fed Variability.
Drug Delivery and Translational Research 2024, 14, 1218–1231.
https://doi.org/10.1007/s13346-023-01453-1
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Hedaoo, A.; Khairnar, P.; Vambhurkar, G.; Srinivasarao, D. A.; Negi, M.; Shinde, A.; Srivastava, S.
Unveiling the Potential of Inorganic Nanoarchitecture-Mediated Photothermal Therapy: An Illustration on Melanoma.
European Polymer Journal 2024, 216, 113282.
https://doi.org/10.1016/j.eurpolymj.2024.113282
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Chaudhuri, A.; Kumar, D. N.; Srivastava, S. K.; Kumar, D.; Patil, U. K.; Parmar, A. S.; Singh, S.; Agrawal, A. K.
Combinatorial Delivery of Docetaxel- and Erlotinib-Loaded Functionalized Nanostructured Lipid Carriers for the Treatment of Triple-Negative Breast Cancer Using Quality-by-Design Approach.
Pharmaceutics 2024, 16.
https://doi.org/10.3390/pharmaceutics16070926
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Pandey, P.; Arya, D. K.; Deepak, P.; Ali, D.; Alarifi, S.; Srivastava, S.; Lavasanifar, A.; Rajinikanth, P. S.
αvβ3 Integrin and Folate-Targeted pH-Sensitive Liposomes with Dual Ligand Modification for Metastatic Breast Cancer Treatment.
Bioengineering 2024, 11.
https://doi.org/10.3390/bioengineering11080800
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Famta, P.; Shah, S.; Sharma, A.; Pandey, G.; Vambhurkar, G.; Srinivasarao, D. A.; Asthana, A.; Kumar, B. K.; Srivastava, S.
Exploration of Multi-Layered Nanofiber Adjuvant Implants of Doxorubicin and Resveratrol to Prevent Post-Surgery Tumor Recurrence and Invasion.
Journal of Drug Delivery Science and Technology 2024, 99, 105977.
https://doi.org/10.1016/j.jddst.2024.105977
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Singh, G.; Sikder, A.; Singh, S. B.; Srivastava, S.; Khatri, D. K.
Drug Delivery Strategies in Parkinson’s Disease.
Drug Delivery Strategies in Neurological Disorders: Challenges and Opportunities 2024, 305–324.
https://doi.org/10.1007/978-981-99-6807-7_13
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Mourya, A.; Famta, P.; Shah, S.; Srinivasarao, D. A.; Sharma, A.; Vambhurkar, G.; Bojja, B.; Arya, S.; Devanagan, P.; Prasad, S. B.; Shinde, A.; Singh, G.; Khatri, D. K.; Srivastava, S.; Madan, J.
Raloxifene Loaded D-α-Tocopherol Polyethylene Glycol 1000 Succinate Stabilized Poly(ε-Caprolactone) Nanoparticles Augmented Drug Delivery and Apoptosis in Breast Cancer Cells.
Journal of Drug Delivery Science and Technology 2024, 92, 105399.
https://doi.org/10.1016/j.jddst.2024.105399
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Sikder, A.; Bagasariya, D.; Shah, S.; Famta, P.; Kashikar, R.; Kotha, A. K.; Johnson, K. R.; Archer, B. P.; Chougule, M. B.; Singh, S. B.; Srivastava, S.
Polymers in Advanced Drug and Gene Delivery.
Polymers in Pharmaceutical and Biomedical Applications: Fundamentals, Selection and Preparation 2024, 291–332.
https://doi.org/10.1016/B978-0-323-95496-9.00008-9
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Palepu, M. S. K.; Bhalerao, H. A.; Sonti, R.; Dandekar, M. P.
Faecalibacterium prausnitzii, FOS and GOS Loaded Synbiotic Reverses Treatment-Resistant Depression in Rats: Restoration of Gut-Brain Crosstalk.
European Journal of Pharmacology 2024, 983, 176960.
https://doi.org/10.1016/j.ejphar.2024.176960
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Shekh, S.; Dhannura, S.; Dhurjad, P.; Ravali, C.; Spoorti, M. M.; Kakkat, S.; Vijayasarathy, M.; Sonti, R.; Gowd, K. H.
Structure-Aided Function Assignment to the Transcriptomic Conopeptide Am931.
Toxicon 2024, 250, 108087.
https://doi.org/10.1016/j.toxicon.2024.108087
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Dhannura, S.; Shekh, S.; Dhurjad, P.; Dolle, A.; Kakkat, S.; Vishwajyoth; Vijayasarathy, M.; Sonti, R.; Gowd, K. H.
Redox-Active Conopeptide Li520 Has Evolved to Catalyze Oxidative Folding of Conotoxins.
ACS Omega 2024, 9, 36.
https://doi.org/10.1021/acsomega.4c01028
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Reddy, G. N.; Jogvanshi, A.; Reddy, D. S.; Chenkual, L.; Sonti, R.
DoE-Assisted HPLC Method Development and Validation of Enzalutamide and Repaglinide in Rat Plasma.
Bioanalysis 2024, 8, 1.
https://doi.org/10.1080/17576180.2024.2383070
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Dannarm, S. R.; Kalan, P.; Ganta, B.; Reddy, G. N.; Sonti, R.
Study on Hydrolytic, Oxidative and Photolytic Degradation Behaviour of Anticancer Drug Sonidegib: Characterization of the Products by UHPLC-Q-TOF-MS/MS, 2D NMR and In Silico Toxicity Assessment.
Journal of Environmental Chemical Engineering 2024, 12, 114111.
https://doi.org/10.1016/j.jece.2024.114111
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Sen, S.; Ganta, B.; Rachel, V. N.; Gogikar, S. K.; Singh, V.; Sonti, R.; Dikundwar, A. G.
Mapping Advantages and Challenges in Analytical Development for Fixed Dose Combination Products: A Review.
Journal of Pharmaceutical Sciences 2024, 113, 2028.
https://doi.org/10.1016/j.xphs.2024.04.025
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Yadav, R.; Bhawale, R.; Srivastava, V.; Pardhi, E.; Bhalerao, H. A.; Sonti, R.; Mehra, N. K.
Innovative Nanoparticulate Strategies in Colon Cancer Treatment: A Paradigm Shift.
AAPS PharmSciTech 2024, 25, 52.
https://doi.org/10.1016/j.xphs.2024.04.025
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Palepu, M. S. K.; Gajula, S. N. R.; Malleshwari, K.; Sonti, R.; Dandekar, M. P.
SCFAs Supplementation Rescues Anxiety- and Depression-Like Phenotypes Generated by Fecal Engraftment of Treatment-Resistant Depression Rats.
ACS Chemical Neuroscience 2024, 15, 1010.
https://doi.org/10.1021/acschemneuro.3c00727
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Paladini, J.; Maier, A.; Habazettl, J. M.; Hertel, I.; Sonti, R.; Grzesiek, S.
The Molecular Basis of Abelson Kinase Regulation by Its αI-Helix.
eLife 2024.
https://doi.org/10.1101/2023.10.04.560671
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Dannarm, R. S.; Dharipally, H.; Reddy, G. N.; Ali, N.; Sonti, R.
Study on the Hydrolytic Degradation Behaviour of Bictegravir by LC-PDA-Q/TOF-MS/MS NMR and In Silico Toxicity Assessment.
Journal of Pharmaceutical and Biomedical Analysis 2024, 239, 115909.
https://doi.org/10.1016/j.jpba.2023.115909
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Mukhopadhyay, N.; Ahmed, R.; Mishra, K.; Sandbhor, R.; Sharma, R. J.; Kaki, V. R.
A Validated, Precise TLC-Densitometry Method for Simultaneous Quantification of Mahanimbine and Koenimbine in Marketed Herbal Formulations.
Future Journal of Pharmaceutical Sciences 2024, 10 (1), 23.
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Makhal, P. N.; Dayare, L. N.; Chilvery, S.; Devi, P.; Shaikh, A. S.; Sharma, A.; Negi, A.; Godugu, C.; Kaki, V. R.
Synthesis, Biological Evaluation, and Molecular Docking Studies of Novel N-Substituted Piperazine-Tethered Thiophene-3-Carboxamide Selenides as Potent Antiproliferative Agents.
Bioorganic Chemistry 2024, 151, 107677.
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Arora, S.; Thakur, S.; Kaki, V. R.; Kumar, R.
Design and Efficient Synthesis of New 4-Amino-Substituted 2-(4-Bromobenzyl)-5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidines of Anticancer Interest and Their In Silico Study.
Synthesis 2024, 10.1055/a-2367-1675.
https://doi.org/10.1055/a-2367-1675
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Mukhopadhyay, N.; Mishra, K.; Ahmed, R.; Sandbhor, R.; Sharma, R. J.; Kaki, V. R.
Determination of Mahanimbine from Murraya koenigii, Collected from Different Geographical Regions of India, by TLC-Densitometry.
Journal of Analytical Chemistry 2024, 79 (8), 1121–1131.
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Katta, C. B.; Bahuguna, D.; Veerabomma, H.; Gollapalli, S.; Shaikh, A. S.; Bhale, N. A.; Dikundwar, A. G.; Kaki, V. R.; Singh, P. K.; Madan, J.
Naringenin-Zinc Oxide Nanocomposites Amalgamated Polymeric Gel Augmented Drug Delivery and Attenuated Experimental Cutaneous Candidiasis in Balb/c Mice: In Vitro and In Vivo Studies.
AAPS PharmSciTech 2024, 25 (5), 130.
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Rahman, Z.; Shaikh, A. S.; Kaki, V. R.; Dandekar, M. P.
Oxyberberine Protects Middle Cerebral Artery Occlusion Triggered Cerebral Injury Through TLR4/NLRP3 Pathway in Rats.
Journal of Chemical Neuroanatomy 2024, 136, 102393.
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Makhal, P. N.; Shaikh, A. S.; Dayare, L. N.; Kaki, V. R.
Research Philosophy, Ethics, and Environmental Aspects.
Principles of Research Methodology and Ethics in Pharmaceutical Sciences 2024, 214–236. (Book Chapter)
- Development of naphthalimide hydrazide derivatives as potent antibacterial agents against carbapenem-resistant A. baumannii. RSC Medicinal Chemistry 15, no. 12 (2024): 4011–4017. Rana P, Maitra R, Saxena D, Akhir A, Vadakattu M, Kalam A, Joshi SV, Parupalli R, Vasundhra Bhandari, Madhavi YV, Dasgupta A, Chopra S, and Nanduri S. https://doi.org/10.1039/d4md00368c
- Molecular docking and molecular dynamics studies of natural products unravel potential inhibitors against OmpA of Acinetobacter baumannii. Journal of Biomolecular Structure and Dynamics 42, no. 17 (2024): 9064–9075. Singothu S, Devsani N, Jahidha Begum P, Maddi D, and Bhandari V. https://doi.org/10.1080/07391102.2023.2250446
- Manifesting the Dasatinib-gallic acid co-amorphous system to augment anticancer potential: Physicochemical characterization, in silico molecular simulation, ex vivo permeability, and in vitro efficacy. International Journal of Pharmaceutics 665 (2024): 124672. Kanp T, Dhuri A, Aalhate M, Mahajan S, Munagalasetty S, Sah SK, Kaity S, Sharma B, Vasundhra Bhandari, and Singh PK. https://doi.org/10.1016/j.ijpharm.2024.124672
- MMV 1804559 is a potential antistaphylococcal and antibiofilm agent targeting the clfA gene of Staphylococcus aureus. Journal of Applied Microbiology 135, no. 11 (2024): lxae276. Brahma U, Singothu S, Suresh A, Vemula D, Munagalasetty S, Sharma P, and Vasundhra Bhandari. https://doi.org/10.1093/jambio/lxae276
- In-silico investigation of E8 surface protein of the monkeypox virus to identify potential therapeutic agents. Journal of Biomolecular Structure and Dynamics 42, no. 16 (2024): 8242–8255. Podduturi S, Vemula D, Singothu S, and Bhandari V. https://doi.org/10.1080/07391102.2023.2245041
- Discovery of Potential Therapeutic Targets in Multi-Drug Resistant Pseudomonas aeruginosa: An Integrative Computational Analysis Spotlighting Proteins. (2024). Vemula D and Vasundhra Bhandari. https://doi.org/10.21203/rs.3.rs-4531708/v1
- Enhancing breast cancer treatment: Comprehensive study of gefitinib-loaded poloxamer 407/TPGS mixed micelles through design, development, in-silico modelling, in-vitro testing, and ex-vivo characterization. International Journal of Pharmaceutics 657 (2024): 124109. Chary PS, Bansode A, Rajana N, Bhavana V, Singothu S, Sharma A, Guru SK, Vasundhra Bhandari, and Mehra NK. https://doi.org/10.1016/j.ijpharm.2024.124109
- Influence of chlorpyrifos and endosulfan and their metabolites on the virulence of Helicobacter pylori. Environmental Pollution 347 (2024): 123676. Singh S, Varshney N, Singothu S, Vasundhra Bhandari, and Hem Chandra. https://doi.org/10.1016/j.envpol.2024.123676
- Epidrugs: alternative chemotherapy targeting Theileria annulata schizont stage parasites. Microbiology Spectrum 12 (2024): e03258-23. Kamble S, Singh S, Suresh A, Singothu S, Dandasena D, Bhandari V, and Sharma P. https://doi.org/10.1128/spectrum.03258-23
- Fabrication of β-cyclodextrin and 2-hydroxypropyl-β-cyclodextrin inclusion complexes of Palbociclib: physicochemical characterization, solubility enhancement, in-silico studies, in vitro assessment in MDA-MB-231 cell line. Journal of Molecular Liquids 399 (2024): 124458. Paul P, Gupta U, Kumar R, Munagalasetty S, Padhy HP, Nair R, Mahajan S et al. https://doi.org/10.1016/j.molliq.2024.124458
- Repurposing of Food and Drug Administration (FDA) approved library to identify a potential inhibitor of trypanothione synthetase for developing an antileishmanial agent. Heliyon 10, no. 6 (2024). Vemula D, Mohanty S, and Vasundhra Bhandari. https://doi.org/10.1016/j.heliyon.2024.e27602
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Forced Degradation of an Anticancer Drug Apalutamide: Impurity Profiling and Structure Elucidation Study.
Chromatographia. 2024; 87(1):71–82.
Sapkal R, Quadri S, Mahajan R, Padhy HP, Asthana A, Samanthula G, and Dikundwar AG.
https://doi.org/10.1007/s10337-023-04294-9
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Investigation on Photo-Isomeric Impurity of Roxadustat: Structure Conformation, Physicochemical Characterization, Interconversion Feasibility and In Vitro Toxicological Evaluation.
Journal of Molecular Structure. 2024; 1298:137017.
Mahajan R, Sharma A, Patra B, Mani L, Grover P, Kumar S, et al.
https://doi.org/10.1016/j.molstruc.2023.137017
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Integrative Analysis of Tepotinib Forced Degradation: Combining In Silico and Liquid Chromatography–Quadrupole Time-of-Flight Tandem Mass Spectrometry Approaches for Structural Elucidation.
Separation Science Plus. 2024; 7(4):2300227.
Mahajan R, Bishnani A, Sapkal R, Dikundwar AG, Gananadhamu S, and Asthana A.
https://doi.org/10.1002/sscp.202300227
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Synthon Approach in Crystal Engineering to Modulate Physicochemical Properties in Organic Salts of Chlorpropamide.
Molecular Pharmaceutics. 2024; 21(6):2894–2907.
Menon AM, Sidhartha NN, Shruti I, Suresh A, Meena R, Dikundwar AG, and Chopra D.
https://doi.org/10.1021/acs.molpharmaceut.4c00043
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Naringenin–Zinc Oxide Nanocomposites Amalgamated Polymeric Gel Augmented Drug Delivery and Attenuated Experimental Cutaneous Candidiasis in BALB/c Mice: In Vitro and In Vivo Studies.
AAPS PharmSciTech. 2024; 25(5):130.
Katta CB, Bahuguna D, Veerabomma H, Gollapalli S, Shaikh AS, Bhale NA, et al.
https://doi.org/10.1208/s12249-024-02841-7
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Multistrain Probiotics with Fructooligosaccharides Improve Middle Cerebral Artery Occlusion–Driven Neurological Deficits by Revamping the Microbiota–Gut–Brain Axis.
Probiotics and Antimicrobial Proteins. 2024; 16(4):1251–1269.
Rahman Z, Bhale NA, Dikundwar AG, and Dandekar MP.
https://doi.org/10.1007/s12602-023-10109-y
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Mapping Advantages and Challenges in Analytical Development for Fixed-Dose Combination Products: A Review.
Journal of Pharmaceutical Sciences. 2024; 113(8):2028–2043.
Sen S, Ganta B, Rachel VN, Gogikar SK, Singh V, Sonti R, and Dikundwar AG.
https://doi.org/10.1016/j.xphs.2024.04.025
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Understanding Molecular Mechanisms behind the Anti-Inflammatory Effects of Machilus macrantha (Gulmavu) by Network Pharmacology and Molecular Modeling Approach.
Journal of Computational Biophysics and Chemistry. 2025; 24(8):985–1007.
Mukhopadhyay N, Sen S, Kumar A, Sandbhor R, Dikundwar AG, and Kaki VR.
https://doi.org/10.21203/rs.3.rs-5288974/v1
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Photoresponsive Halogen-Bonded Complexes of 1,3,5-Trifluoro-2,4,6-triiodobenzene and Alkoxyazopyridine Derivatives Based on Py–N···I Interactions: Synthesis, Structural, and Theoretical Insights.
Crystal Growth & Design. 2024; 24(22):9391–9402.
Thakur JS, Dash O, Ingle KS, Lahoti KB, Sudheendranath A, Bhale NA, et al.
https://doi.org/10.1021/acs.cgd.4c00781
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Three Strikingly Different Crystal Habits of Tadalafil: Design, Characterization, Pharmaceutical Performance, and Computational Studies.
Molecular Pharmaceutics. 2024; 21(12):6234–6244.
Bhale NA, Shah S, Jahnavi AS, Vishwakarma A, Thakur TS, Thomas SP, et al.
https://doi.org/10.1021/acs.molpharmaceut.4c00601
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Bioanalytical Method Development and Validation of Docetaxel and Carvacrol in Mice Plasma Using LC-QqQ-MS/MS.
European Journal of Mass Spectrometry. 2024; 30(5–6):235–245.
Gogikar SK, Sen S, Daravath S, Aalhate M, Mahajan S, Ateeq MAM, et al.
https://doi.org/10.1177/14690667241289
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Coamorphous Systems of Rebamipide: Selection of Amino Acid Coformers Based on Protein–Ligand Docking, In Vitro Assessment, and Study of Interactions by Computational and Multivariate Analysis.
International Journal of Pharmaceutics. 2024; 667:124955.
Sharma A, Dey S, Sidhartha NN, Shah S, Sapkal R, Srivastava S, and Dikundwar AG.
https://doi.org/10.1016/j.ijpharm.2024.124955
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Bakchi, B.; Maddipatla, S.; Gottemukkala, S.; Raut, S.; Ahmad, M. N.; Imran, M.; Saxena, D.; Maitra, R.; Agnivesh, P. K.; Kalia, N. P.; Nanduri, S.; Dasgupta, A.; Chopra, S.; Yaddanapudi, V. M.
Benzyl/phenyl-1,2,3-Triazole Tethered 3-Acetyl Coumarins as Potential Drug-Resistant Antitubercular Agents: Synthesis, Biology, and In Silico Investigations as Mtb DNA Gyrase Inhibitors.
ChemistrySelect 2024, 9(39), e202402316.
https://doi.org/10.1002/slct.202402316
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Bakchi, B.; Devabattula, G.; Maddipatla, S.; Singampalli, A.; Porna, D. K.; Nanduri, D. S.; Sharma, A.; Godugu, D. C.; Yaddanapudi, D. V. M.
New Indole-Based Phenylthiazolyl-2, 4-dihydropyrazolones as Tubulin Polymerization Inhibitors: Multicomponent Synthesis, Cytotoxicity Evaluation, and In Silico Studies.
ChemMedChem 2024, 20(5), e202400817.
https://doi.org/10.1002/cmdc.202400817
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Malasala, S.; Polomani, A.; Gour, J.; Nanduri, S.
Candida antarctica lipase B catalyzed condensation reactions: Water mediated chemo-enzymatic synthesis of different heterocycles.
Tetrahedron Lett. 2024, 153, 155371.
https://doi.org/10.1016/j.tetlet.2024.155371
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Kalam, A.; Ghouse, S. M.; Joshi, S. V.; Tamang, N.; Sahu, N. R.; Yaddanapudi, M. V.; Nanduri, S.
Synthetic Approaches toward Dabigatran Etexilate, an Oral Anticoagulant Drug.
Org. Process Res. Dev. 2024, 28(9), 3509–3523.
https://doi.org/10.1021/acs.oprd.4c00233
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Rana, P.; Supriya, M. S.; Kalam, A.; Eedulakanti, C.; Kaul, G.; Akhir, A.; Sindhuja, R. H.; Roy, A.; Agnivesh, P. K.; Saxena, D.; Ahmad, M. N.; Madhavi, Y.; Dasgupta, A.; Kalia, N. P.; Nagesh, N.; Chopra, S.; Nanduri, S.
Synthesis and antibacterial evaluation of new naphthalimide-coumarin hybrids against multidrug-resistant S. aureus and M. tuberculosis.
J. Mol. Struct. 2024, 1307, 137957.
https://doi.org/10.1016/j.molstruc.2024.137957
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Maddipatla, S.; Bakchi, B.; Gadhave, R. R.; Ammara, A.; Sau, S.; Rani, B.; Nanduri, S.; Kalia, N. P.; Supuran, C. T.; Yaddanapudi, V. M.
Exploring rhodanine linked enamine–carbohydrazide derivatives as mycobacterial carbonic anhydrase inhibitors: Design, synthesis, biological evaluation, and molecular docking studies.
Arch. Pharm. 2024, 357(7), 2400064.
https://doi.org/10.1002/ardp.202400064
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Tamang, N.; Inabathina, Y.; Mavileti, S. K.; Sripada, L.; Nanduri, S.; Golakoti, N. R.; Karanam, B.
(3, 19)-4-Bromobenzylidene-isoandrographolide Induces Apoptosis and Causes Loss of Mitochondrial Membrane Potential in MCF-7 Breast Cancer Cells.
ChemistrySelect 2023, 9(3), e202302498.
https://doi.org/10.1002/slct.202302498
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Rokkam, S. K.; Bhujel, M.; Jain, D.; Sripada, L.; Nanduri, S.; Bajaj, A.; Golakoti, N. R.
Synthesis of novel pyrazole acetals of andrographolide and isoandrographolide as potent anticancer agents.
RSC Adv. 2024, 14, 26625–26636.
https://doi.org/10.1039/d4ra00547c
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Rana, P.; Maitra, R.; Saxena, D.; Akhir, A.; Vadakattu, M.; Kalam, A.; Joshi, S. V.; Parupalli, R.; Bhandari, V.; Madhavi, Y.; Dasgupta, A.; Chopra, S.; Nanduri, S.
Development of naphthalimide hydrazide derivatives as potent antibacterial agents against carbapenem-resistant A. baumannii.
RSC Med. Chem. 2024, 15(12), 4011–4017.
https://doi.org/10.1039/d4md00368c
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Rana, P.; Parupalli, R.; Akhir, A.; Saxena, D.; Maitra, R.; Imran, M.; Malik, P.; Ghouse, S. M.; Joshi, S. V.; Srikanth, D.; Madhavi, Y.; Dasgupta, A.; Chopra, S.; Nanduri, S.
Synthesis and biological evaluation of new naphthalimide–thiourea derivatives as potent antimicrobial agents active against multidrug-resistant Staphylococcus aureus and Mycobacterium tuberculosis.
RSC Med. Chem. 2024, 15(4), 1381–1391.
https://doi.org/10.1039/d4md00062e
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Bakchi, B.; Maddipatla, S.; Gupta, K.; Singampalli, A.; Saxena, D.; Maitra, R.; Agnivesh, P. K.; Kalia, N. P.; Nanduri, S.; Chopra, S.; Yaddanapudi, V. M.
Facile one-pot synthesis of N-pyridinylaminonaphthol derivatives and their antibacterial evaluation against multidrug-resistant Staphylococcus aureus.
Arch. Pharm. 2024, 357(11), e2400358.
https://doi.org/10.1002/ardp.202400358
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Mohd Rabi Bazaz; Amit Asthana; Manoj P. Dandekar
Chitosan revokes controlled-cortical impact-generated neurological aberrations in circadian-disrupted mice via the TLR4-NLRP3 axis.
European Journal of Pharmacology 2024, 969, 176436.
https://doi.org/10.1016/j.ejphar.2024.176436
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Arjun Jayachandran; Shahila Parween; Amit Asthana; Shantimoy Kar
Microfluidics-Based Blood Typing Devices: An In-Depth Overview.
ACS Applied Bio Materials 2024, 7(1), 59–79.
https://doi.org/10.1021/acsabm.3c00995
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Rupali Mahajan; Abhishek Sharma; Bhagyashree Patra; Lijo Mani; Parul Grover; Sandeep Kumar; Santosh Kumar Guru; Gananadhamu Samanthula; Amol G. Dikundwar; Amit Asthana
Investigation of the photo-isomeric impurity of Roxadustat: Structure conformation, physicochemical characterization, interconversion feasibility, and in vitro toxicological evaluation.
Journal of Molecular Structure 2024, 1298, 137017.
https://doi.org/10.1016/j.molstruc.2023.137017
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Rupali Mahajan; Aman Bishnani; Rekha Sapkal; Amol G. Dikundwar; Samanthula Gananadhamu; Amit Asthana
Integrative analysis of tepotinib forced degradation: Combining in silico and liquid chromatography-quadrupole time-of-flight-tandem mass spectrometry approaches for structural elucidation.
Separation Science Plus 2024, 7(4), 2300227.
https://doi.org/10.1002/sscp.202300227
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Mahajan R; Chandragiri ST; Borse V; Samanthula G; Asthana A
Reverse-phase high-performance liquid chromatography methodology for film-forming mafenide spray: Compatibility, assay, and in-vitro release evaluation using Franz vertical diffusion cell apparatus.
Separation Science Plus 2024, 7, 2300148.
https://doi.org/10.1002/sscp.202300148
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Jain, Sandli; Kamble, Adarsh; Dr. B. Lakshmi; Kishore, Sai
Relationship Between Social Media Addiction and Depression Among Teenagers.
International Journal of Advance Research and Innovative Ideas in Education 2024, 10(1), 1636–1644.
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Lulu, Piyush; Kudatarkar, Anushree; Dr. B. Lakshmi; Balabadrapatruni, V.; Saikishore, V.
Impact of e-pharmacies on population.
International Journal of Advance Research and Innovative Ideas in Education 2024, 10(1), 1843–1854.
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Vishvajit T. Nimbalkar; Parmita P. Tayade; B. Lakshmi; Sai Kishore V.
Effect of mobile gaming on population–a review.
International Journal of Advance Research and Innovative Ideas in Education 2024, 10(1), 301–307.
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Varun Gupta; Payal Kewlani; Siddesh Shewalkar; Dr. B. Lakshmi; Mr. Sai Kishore V.
PLI scheme in medical devices manufacturing.
International Journal of Novel Research and Development 2024, 9(3), a182–a195.
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Vaishnavi Wane; Ankur Nandal; Dr. B. Lakshmi; Saikishore V.
Impact of demonetization on the Indian economy.
International Journal of Creative Research Thoughts 2024, 12(2), February 2024.
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Pranav Tiwari; Nishtha Maheshwari; Dr. B. Lakshmi; Sai Kishore V.
Consumer Protection for Indian Pharma Industry.
International Journal of Novel Research and Development 2024, 9(3), a215–a222.
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Vaishnavi Ghadge; Pritam Jaiswar; Dr. B. Lakshmi; SaiKishore V.
How to implement omnichannel HCP engagement across markets.
International Journal of Novel Research and Development 2024, 9(3), b446–b458.