Name: Dr. Sai Sudhir Venkatesh Associate Professor sai.sudhir@niperhyd.ac.in ; saisudhirkv@gmail.com ;

ADDRESS, ROOM NO

Department of Chemical Sciences​
NIPER Hyderabad
Hyderabad – 500037, TS, INDIA

QUALIFICATION: (REVERSE CHRONOLOGICAL ORDER)

• Alexander von Humboldt (AvH) Postdoctoral fellow at university of Leipzig, Germany (2010-2012)
• Postdoctoral fellow @ Astrazeneca India Pvt Ltd, Bangalore (2010)
• PhD (IISc, Bangalore) with Prof. S. Chandrasekaran, Department of Organic Chemistry (2004-2009)
• MSc : Sri Sathya Sai Institute of Higher Learning, Prasanthinilayam, Andhra Pradesh (2002-2004)
• BSc : Sri Sathya Sai Institute of Higher Learning, Prasanthinilayam, Andhra Pradesh (1999-2002)

EXPERIENCE

• Associate Professor (December 2025 - till date), NIPER-Hyderabad
• Senior Principal Investigator: Syngene Scientific Solutions, Genome Valley, Hyderabad (2025)
• Principal Scientific Manager @ Aragen Life Sciences, Bangalore (2022-2025)
• Principal Investigator @ BBRC, Syngene, Bangalore (2018-2022)
• Senior Scientist @ Dr.Reddy’s Laboratories, Hyderabad (2014-2018)
• Associate Research Scientist: AstraZeneca India Pvt Ltd, Bangalore (2013-2014)

COURSES HANDLING(PHD/M.S(PHARM))

• Structure elucidation (NP-640)


• Logic in organic synthesis - 1 (MC-620)


• Logic in organic synthesis - 2

PHD STUDENTS/MASTERS STUDENTS

• Will be updated shortly!

AWARDS / HONOURS

• All India 9th rank (99.73 percentile) in GATE Chemistry (Graduate Aptitude Test in Engineering) 2004.
• University Gold medal for topping in MSc (Chemistry) in 2004 from Sri Sathya Sai Institute of Higher Learning, India.
• First student sent from India for INDIGO Program to work in Germany for 7 months from Oct 2008 to Apr 2009. (Collaborative program between Indian and German universities for organic synthesis)
• Special recognition from Dr.Reddy’s Laboratories for proposing and executing a new route to a complex challenging intermediate of Eribulin (Anti-cancer drug) (Patented)

RESEARCH AREAS/INTEREST

• Development of new synthetic methodologies
• Heterocyclic chemistry
• Asymmetric Synthesis
• Unnatural amino acid chemistry
• Development of new routes to KSM’s and API’s
• Protecting group chemistry

FELLOWSHIPS/GRANTS

• Two-year Humboldt Postdoctoral fellowship from the prestigious Alexander von Humboldt Foundation (AvH), Germany
• Recipient of Junior & Senior Research Fellowships awarded by CSIR.
• Selected for Shyama Prasad Mukherjee fellowship exam in CSIR-JRF held in 2004.

PUBLICATIONS / BOOK CHAPTERS

1. A highly Enantioselective, Regioselective, Organocatalytic Vinylogous Mukaiyama- Michael Reaction. V. Gupta, V. Sai Sudhir, T. Mandal, Ch. Schneider*. Angewandte. Chemie. Int. Ed, 2012, 51, 12609-12612
2. Facile Entry to 4,5,6,7-Tetrahydro[1,2,3]triazolo[1,5-a]pyrazin-6-ones from Amines and Amino Acids - V. Sai Sudhir, R. B. Nasir Baig, S. Chandrasekaran.European Journal of Organic Chemistry, 2008, 2423-2429
3. Facile Entry into Triazole fused Heterocycles from Sulfamidate Derived Azido-alkynes- V. Sai Sudhir, N. Y. Phani Kumar, R. B. Nasir Baig, S. Chandrasekaran; J. Org. Chem. 2009, 74, 7588-7591
4. Simple and Efficient Synthesis of allo and threo- 3,3'-dimethylcystine Derivatives in Enantiomerically Pure form - R. B. Nasir Baig, V. Sai Sudhir, S. Chandrasekaran, Tetrahedron Asymmetry, 2008, 19, 1425-1429
5. Click Chemistry Inspired Synthesis of Novel Ferrocenyl substituted Amino acids and Peptides. - V. Sai Sudhir, Ch. Venkateswarlu, O. T. Muhammed Musthafa, S. Sampath,* S. Chandrasekaran. Eur.J. Org. Chem, 2009, 2120-2129
6. Convenient Synthesis of Ferrocene Conjugates Mediated by Benzyltriethylammonium Tetrathiomolybdate in a Multi-step Tandem Process - V. Sai Sudhir, R. B. Nasir Baig, S. Chandrasekaran* Eur. J. Org. Chem. 2009, 31, 5365-5372
7. Synthesis of β-aminodiselenides and Unnatural Selenoamino acids Mediated by Tetrathiomolybdate - R. B. Nasir Baig. N. Chandrakala, V. Sai Sudhir and S. Chandrasekaran. J. Org. Chem, 2010, 75, 2910-2921
8. Click Chemistry inspired Synthesis of Ferrocene amino acids and other derivatives - V. Sai Sudhir, N. Y. Phani Kumar, S. Chandrasekaran. Tetrahedron, 2010, 66, 1327-1334
9. "10 Years of Click Chemistry: Synthesis and Applications of Ferrocene Derived Triazoles" V. Ganesh, V. Sai Sudhir, K. Taraknath and S. Chandrasekaran. Chem. Asian. J, 2011, 6, 2670- 2694 (Focus Review)
10. Discovery of novel glitazones incorporated with phenylalanine and tyrosine: Synthesis, antidiabetic activity and structure-activity relationships-Prashantha Kumar B. R, Nasir R. Baig, V. Sai Sudhir and Nanjan M. Joghee Bioorganic Chemistry, 2012, 45, 12-28.
11. Transition metal catalyzed C-H activation for the synthesis of medicinally relavant molecules: A Review; Debjit Basu, Sarvesh Kumar, V Sai Sudhir and Rakeshwar Bandicchor; J. Chem. Sci, 2018, 130, 71
12. A Novel Method for the Synthesis of Thioacetates Using Benzyltriethylammonium Tetrathiomolybdate and Acetic Anhydride - R. B. Nasir Baig, V. Sai Sudhir, S. Chandrasekaran. Synlett, 2008, 17
13. Facile Synthesis of β-amino disulfides, Cystines and their Direct Incorporation into Peptides - R. B. Nasir Baig. , K. Kanimozhi Catherine, V. Sai Sudhir and S. Chandrasekaran. Synlett, 2009, 8, 1227.

PATENTS

• Process for preparation of Eribulin and intermediates thereof International Application No: PCT/IB2016/056097. Publication No: WO/2017/064627
• Process for preparation of Eribulin and intermediates thereof International Application No: PCT/IB2017/053082. Publication No: WO/2017/203459

INVITED TALKS

April 19, 2025, “Process development of Eribulin intermediate-A case of complex Generics” at JSS acadmy of higher education and research, Mysore, karnataka

ADDITIONAL RESPONSIBILITIES

Will be updated shortly!

ANY OTHER INFORMATION

Will be updated shortly!